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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: APOBEC3G All Species: 4.55
Human Site: Y181 Identified Species: 16.67
UniProt: Q9HC16 Number Species: 6
    Phosphosite Substitution
    Charge Score: -0.33
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HC16 NP_001006667.1 384 46408 Y181 P W N N L P K Y Y I L L H I M
Chimpanzee Pan troglodytes Q7YR24 384 46070 Y181 P W N N L P K Y Y I L L H I M
Rhesus Macaque Macaca mulatta Q7YR23 370 43595 K202 F T S N F N N K P W V S G Q H
Dog Lupus familis XP_852783 197 22961 C34 N P S K T Y L C Y Q V E L S D
Cat Felis silvestris
Mouse Mus musculus Q99J72 429 50929 Q189 L L T N F R Y Q D S K L Q E I
Rat Rattus norvegicus P60705 429 51066 Q189 L L T N F R Y Q D S K L Q E I
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_416483 198 23812 R35 Y L C Y V V K R R D S A T S C
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95.8 73.6 25.7 N.A. 30.7 31.2 N.A. N.A. 20 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 97.4 81.7 35.9 N.A. 46.3 47.7 N.A. N.A. 30.2 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 6.6 6.6 N.A. 13.3 13.3 N.A. N.A. 6.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 20 20 N.A. 20 20 N.A. N.A. 13.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 15 0 0 0 % A
% Cys: 0 0 15 0 0 0 0 15 0 0 0 0 0 0 15 % C
% Asp: 0 0 0 0 0 0 0 0 29 15 0 0 0 0 15 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 15 0 29 0 % E
% Phe: 15 0 0 0 43 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 15 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 29 0 15 % H
% Ile: 0 0 0 0 0 0 0 0 0 29 0 0 0 29 29 % I
% Lys: 0 0 0 15 0 0 43 15 0 0 29 0 0 0 0 % K
% Leu: 29 43 0 0 29 0 15 0 0 0 29 58 15 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 29 % M
% Asn: 15 0 29 72 0 15 15 0 0 0 0 0 0 0 0 % N
% Pro: 29 15 0 0 0 29 0 0 15 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 29 0 15 0 0 29 15 0 % Q
% Arg: 0 0 0 0 0 29 0 15 15 0 0 0 0 0 0 % R
% Ser: 0 0 29 0 0 0 0 0 0 29 15 15 0 29 0 % S
% Thr: 0 15 29 0 15 0 0 0 0 0 0 0 15 0 0 % T
% Val: 0 0 0 0 15 15 0 0 0 0 29 0 0 0 0 % V
% Trp: 0 29 0 0 0 0 0 0 0 15 0 0 0 0 0 % W
% Tyr: 15 0 0 15 0 15 29 29 43 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _